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Nicotine exposure during pregnancy nearly twice as high as reported

The study reveals a significant gap between the number of local, pregnant mothers who report smoking during pregnancy and the number who test positive for nicotine exposure. "This is extremely important new information for us as we work to better understand risk factors for preterm birth," said Jim Greenberg, MD, director of the Perinatal Institute at Cincinnati Children's and senior author of the study. "We have long suspected that smoking status during pregnancy is under-reported, but now we know just how many women struggle to quit smoking when they are pregnant." The study, published online in the  Journal of Perinatology , detected high-level nicotine exposure for 16.5 percent of women in the study and low-level exposure for an additional 7.5 percent. Only 8.6 percent, however, admitted to using cigarettes. The study suggests that tools researchers use to estimate nicotine use do not accurately capture all means of nicotine exposure, including e-cigar...

Teen vaping could reverse progress in the control of tobacco

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The information counsel that no less than a number of the teenagers who're vaping wouldn't have smoked cigarettes. Credit score: USC Youngsters's Well being Research (https://healthstudy.usc.edu/) A brand new USC research debunks the favored perception that digital cigarettes are merely an alternative choice to cigarettes amongst teenagers. As a substitute, the research means that some teenagers who by no means would have smoked cigarettes at the moment are vaping. E-cigarettes, which entered the U.S. market in 2007, vaporize liquids which will or might not include nicotine. In 2011, about 1.5 p.c of excessive schoolers had vaped up to now 30 days, in line with the Nationwide Youth Tobacco Survey. 4 years later, that quantity skyrocketed to 16 p.c. A USC research of 5,490 highschool juniors and seniors reveals tobacco use amongst teenagers in Southern California is on the rise. In 2014, about 14 p.c of 12th-graders mentioned they'd both smoked ...

Doctors shouldn't routinely recommend e-cigarettes to smokers

The researchers point out in a commentary published in  Annals of Family Medicine  that existing treatments are more effective than e-cigarettes to help people quit smoking, there are professional ethics concerns about providers who recommend them, and there is no strong evidence that e-cigarettes are safe. "Providers should not routinely recommend e-cigarettes to patients until we have far more data on their safety and effectiveness compared to established, FDA -approved medications," said Adam O. Goldstein, MD, MPH, a UNC Lineberger Comprehensive Cancer Center member and professor in the UNC School of Medicine. "There are very few therapeutic devices that we recommend that aren't regulated, that have potential and real side effects, and that are addictive. There are safer and more effective smoking cessation products for the same condition." The researchers described notable safety and health concerns about e-cigarettes. Batteries inside e-cigarettes hav...

Study finds differing treatment options for women smokers

The study, "Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis," which reviewed and analyzed evidence from over 14,000 cigarette smokers participating in 28 clinical trials for nicotine patch, varenicline and bupropion, found that across the trials women who were given varenicline were much more likely to quit smoking than women who were given nicotine patch or bupropion. By contrast, among men there were no differences in the likelihood of successfully quitting smoking when given varenicline , bupropion or nicotine patch. While the study found that all three medications helped both women and men quit when compared to placebo, the difference was in the relative benefit of the three medications. Clinical trial data consistently show that taking medications can help smokers quit. Some may help more than others, and for women the best choice may be varenicline. "Before our study, research had shown that among the choices...

Drug-use may hamper moral judgment

Research has shown that stimulant users often find it difficult to identify other people's emotions, particularly fear, and to show empathy. These aspects play an important role in moral decision making. Other studies have pointed to structural and functional abnormalities in especially the frontal regions of their brains among stimulant users. These areas are engaged when moral judgments have to be made. There is strong link between drug use and criminal behavior, and up to 75 percent of inmates in the US have substance abuse problems. It is not known whether the criminal behavior is in part a result of the drugs' effects on brain function. Kiehl's team is the first to examine how the neural networks and brain functioning of chronic cocaine and methamphetamine users in US jails relate to their ability to evaluate and decide about moral situations or scenarios. Poor judgment about moral situations can lead to poor decision making and subsequent antisocial behavior. ...

Why scientists are calling for experiments on ecstasy

"We've learned a lot about the nervous system from understanding how drugs work in the brain--both therapeutic and illicit drugs," says Robert Malenka, a psychiatrist and neuroscientist at Stanford University. "If we start understanding MDMA's molecular targets better, and the biotech and pharmaceutical industries pay attention, it may lead to the development of drugs that maintain the potential therapeutic effects for disorders like autism or PTSD but have less abuse liability." MDMA is described as an "empathogen," a compound that promotes feelings of empathy and close positive social feelings in users. The drug is a strictly regulated Schedule I compound, along with drugs such as heroin and LSD. However, MDMA's regulated status shouldn't discourage researchers from studying its effects, argue Malenka and coauthor Boris Heifets, also at Stanford. Researchers still don't know exactly how MDMA works in humans, what regions of the...

Public health benefits of e-cigarette use tend to outweigh the harms

The study, published in  Nicotine & Tobacco Research , suggests that "recent claims by some scientists that e-cigarettes are likely to act as a gateway to the use of tobacco products are overstated," says the study's lead author, population scientist David Levy, PhD, a professor of oncology at Georgetown Lombardi Comprehensive Cancer Center . If used instead of smoking, e-cigarettes provide the potential to reduce harm and improve public health, Levy says. But they also have the potential to increase harm if youth who would not have otherwise smoked become cigarette smokers as a direct consequence of first trying e-cigarettes -- the so-called "gateway" hypothesis that has gained favor by some, he says. "Our study indicates that, considering a broad range of reasonable scenarios, e-cigarettes are likely to reduce cigarette smoking and not lead to offsetting increases in harm from the use of e-cigarettes and more deadly cigarettes," Levy says. ...